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Clinical Trials Controversy







Clinical Trials Controversy

Clinical Trials Controversy 06/21/2004 12:40 PM

A clinical trials database may appeal to some. But open access to studies may not be in the interests of drug companies or the public.




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Clinical Trials Controversy

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Patient Recruitment for Clinical Trials


Patient Recruitment for Clinical Trials 02/19/2004 07:30 PM
marcus evans Feb 19 2004 11:14PM GMT

Clinical drug trials 'distorted'


Clinical drug trials 'distorted' 09/09/2004 08:37 PM
More openness is needed over clinical drug trial results to stop them being distorted, leading medical journals say.

"Researchers working for full disclosure
of clinical trials"


"Researchers working for full disclosure
of clinical trials"
08/18/2004 02:52 PM

Clinical Trials Site Demystifies Medical
Jargon


Clinical Trials Site Demystifies Medical
Jargon
08/08/2004 05:40 AM
Clinical Trials Site Demystifies Medical Jargon
http://www.washingtonpost.com/wp-dyn/articles/A19274-2004Jul27.ht ml

ClinicalTrials.gov is a federally funded database of clinical trials, open and accessible to the public. Part of the National Institutes of Health, it provides information about a trial's purpose, who may participate, locations, even phone numbers for more details. Led by Alexa McCray, director of the Lister Hill National Center for Biomedical Communications, the site has been embraced by millions of people trying to puzzle their way through the often Byzantine world of clinical trials. It currently includes information about 11,100 trials, including those carried out by NIH, other federal agencies and private industry. Trained in linguistics, McCray is a strong advocate of distilling complex medical terminology into simple, everyday language. The goal is to help prospective patients make informed choices, after weighing the benefits and risks of taking part in medical trials. Critics complain about the limited scope of the database, particularly when it comes to clinical trials carried out by the private drug industry. The American Medical Association, among others, say pharmaceutical companies should be forced to register details about the opening of a drug trial and its results, something which is currently optional. Some industry officials complain that such a requirement would compromise proprietary information. McCray believes mandatory registration would lead to more effective research. "Patients have the right to this kind of information, whether it's clinical trials data or the latest literature on medical breakthroughs or just getting a better understanding of some condition that you or a family member suffers from."

Vancouver home to burgeoning clinical
trials testing sector


Vancouver home to burgeoning clinical
trials testing sector
06/04/2004 05:35 PM
Business in Vancouver Jun 4 2004 9:59PM GMT

HealthMark Multimedia Announces Grant
from NIH to Develop Onlined Informed
Consent for Clinical Trials


HealthMark Multimedia Announces Grant
from NIH to Develop Onlined Informed
Consent for Clinical Trials
03/14/2005 05:24 PM
HealthMark Multimedia, LLC, has been awarded a National Cancer Institute Small Business Innovation Research (SBIR) grant to produce an online product to facilitate clinical trial investigators in the development of informed consent documents and a media-enhanced information and educational support toward greater informed consent for potential clinical trial subjects. [PRWEB Mar 11, 2005]

LogiXML Reporting Solutions Gain
Momentum as OmniComm Joins Growing
Roster of Key LogiXML Partners in
Pharmaceutical Clinical Trials Industry


LogiXML Reporting Solutions Gain
Momentum as OmniComm Joins Growing
Roster of Key LogiXML Partners in
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04/13/2005 03:26 AM
LogiXML’s LGX Ad Hoc end user reporting product integrated with OmniComm’s TrialMaster to provide powerful reporting/analysis for clinicians; OmniComm Joins Sierra Scientific and Datatrial as LogiXML partners in pharmaceutical clinical trials field [PRWEB Apr 13, 2005]

Clinical Medicine Netprints


Clinical Medicine Netprints 04/14/2005 07:05 AM


Clinical Medicine and Health Research Netprints
http://clinmed.netprints. org/home.dtl

A repository of non-peer reviewed original research. Articles posted on this site have not yet been accepted for publication by a peer reviewed journal. They are presented here mainly for the benefit of fellow researchers. Casual readers should not act on their findings, and journalists should be wary of reporting them. This has been added to Research Resources Subject Tracerâ„¢ Information Blog. This has been added to Academic and Scholar Search Engines and Sources Annotated White Paper. This will be added to Healthcare Resources 2005 Internet MiniGuide.

Where now with clinical computer
systems?


Where now with clinical computer
systems?
11/06/2003 03:01 AM
Royal College of General Practitioners Nov 6 2003 2:17AM ET

Clinical Medicine and Health Research


Clinical Medicine and Health Research 10/30/2003 07:04 AM
Clinical Medicine and Health Research
http://clinmed.netprints. org/home.dtl

A repository of non-peer reviewed original research. Articles posted on this site have not yet been accepted for publication by a peer reviewed journal. They are presented here mainly for the benefit of fellow researchers. Casual readers should not act on their findings, and journalists should be wary of reporting them.

I'm a clinical psychologist with a
relationship problem


I'm a clinical psychologist with a
relationship problem
01/03/2005 10:10 AM
He wants friendship but I want more -- could this be part of a negative pattern?

Prosthetic rat-hippocampus goes into
clinical tests


Prosthetic rat-hippocampus goes into
clinical tests
03/13/2003 10:24 AM
A research lab in California is testing the world's first "brain prosthesis," an artificial hippocampus that interfaces directly with rat-brains. Primates in less than a year.
The job of the hippocampus appears to be to "encode" experiences so they can be stored as long-term memories elsewhere in the brain. "If you lose your hippocampus you only lose the ability to store new memories," says Berger. That offers a relatively simple and safe way to test the device: if someone with the prosthesis regains the ability to store new memories, then it's safe to assume it works.

The inventors of the prosthesis had to overcome three major hurdles. They had to devise a mathematical model of how the hippocampus performs under all possible conditions, build that model into a silicon chip, and then interface the chip with the brain.

No one understands how the hippocampus encodes information. So the team simply copied its behaviour. Slices of rat hippocampus were stimulated with electrical signals, millions of times over, until they could be sure which electrical input produces a corresponding output. Putting the information from various slices together gave the team a mathematical model of the entire hippocampus.

Link Discuss

ID Biomedical Receives Positive Data
From Clinical Testing


ID Biomedical Receives Positive Data
From Clinical Testing
03/22/2005 07:09 PM
BC Technology Mar 22 2005 10:50PM GMT

Optimising the Paradigm for Clinical
Drug Development in Oncology


Optimising the Paradigm for Clinical
Drug Development in Oncology
12/12/2003 09:19 AM
marcus evans Dec 12 2003 8:23AM ET

GlaxoSmithKline to post all clinical
trial results online


GlaxoSmithKline to post all clinical
trial results online
06/20/2004 04:58 AM
Pe.com - Sat Jun 19, 10:46 pm GMT

Drug Makers Support Clinical Trial
Disclosure


Drug Makers Support Clinical Trial
Disclosure
06/18/2004 10:28 PM
Two of the world's largest pharmaceutical companies say results from late-stage clinical trials should be made available to the public, even if they reveal unfavorable information about a drug.

New Eclipsys Clinical Apps Ease Drug
Orders


New Eclipsys Clinical Apps Ease Drug
Orders
03/31/2005 02:58 PM
Latest release reduces the number of clicks physicians need to make to complete an order and automatically adds in billing codes to eliminate additional entries.

Cardiome Reports Final Oxypurinol
Clinical Results


Cardiome Reports Final Oxypurinol
Clinical Results
04/10/2005 05:49 AM
BC Technology Apr 10 2005 9:25AM GMT

Oracle buys clinical trial software
maker


Oracle buys clinical trial software
maker
01/22/2004 02:17 PM

GlaxoSmithKline, facing lawsuit, to post
all clinical results on Internet


GlaxoSmithKline, facing lawsuit, to post
all clinical results on Internet
06/19/2004 09:02 AM
Canadian Press Jun 19 2004 1:12PM GMT

Usage quadruples for Clinical Governance
Support Team web site


Usage quadruples for Clinical Governance
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01/05/2004 03:38 AM
PublicTechnology.net Jan 5 2004 3:11AM ET

Drug Industry Site to Share Some
Clinical Trial Results


Drug Industry Site to Share Some
Clinical Trial Results
09/08/2004 08:52 AM
WASHINGTON (AP) An association that represents the nation's leading drug manufacturers said Tuesday it has created a Web site where companies can list clinical trials they sponsored for drugs approved by the Food and Drug Administration.

VCHRI and Syreon Corporation to Provide
Integrated Clinical Trial Service
Offerings


VCHRI and Syreon Corporation to Provide
Integrated Clinical Trial Service
Offerings
05/21/2004 05:35 PM
BC Technology May 21 2004 9:41PM GMT

AnorMED Announces New HIV Entry
Inhibitor Drug Candidate to Advance to
Phase II Clinical Program


AnorMED Announces New HIV Entry
Inhibitor Drug Candidate to Advance to
Phase II Clinical Program
07/09/2004 05:10 PM
BC Technology Jul 9 2004 9:25PM GMT

Xillix Officially Closes Onco-LIFE
Clinical Trial; Submits Request for
Continued Access to FDA


Xillix Officially Closes Onco-LIFE
Clinical Trial; Submits Request for
Continued Access to FDA
12/30/2003 04:09 PM
BC Technology Dec 30 2003 3:08PM ET

RSS Controversy


RSS Controversy 01/24/2003 12:10 AM
My scraped RSS feeds stroke the wrong cord with someone (see Inluminent & Unsanity) Until sites catch on scraping will be done. I'm but one

The Kos Controversy


The Kos Controversy 04/09/2004 03:55 PM
Markos Moulitsas Zúniga, the webmaster of the Scoop-powered lefty blog Daily Kos, recently made controversial comments regarding the four Americans killed in Falluja. More precisely, he said "screw them." He later posted a clarification of his comments, but stopped short of an apology. So, Instapundit, Tacitus, and many other sites have condemned the comment. Some advertisers have taken their ads off the site, the Kerry campaign took down their link to Daily Kos, and people have generally said "rabble rabble rabble." Tacitus and others have even suggested that Daily Kos should no longer raise money for the Democrats.

"a lot of controversy"


"a lot of controversy" 03/24/2005 04:37 AM

The Konfabulator Controversy


The Konfabulator Controversy 06/30/2004 10:45 PM

inessential.com: Weblog: What should Apple do?: There's a bit of a controversy brewing in Macland about the WWDC conference and the Konfabulator knockoff Apple introduced called Dashboard. The theory is that Apple saw a great third-party app that people loved, and decided it needed to be part of the OS itself.

Apple can’t do everything — they need other developers to make software for OS X too. What concerns me is the message the Dashboard thing sends. It goes like this, "If you come up with a good idea and develop a successful product, we might copy it and bundle it for free with the OS."

The Konfabulator folks, for their part, are having some fun with it, poking fun of the posters that poked fun at Microsoft with a banner on their site that says, "Cupertino [where Apple is based], start your photocopiers!"

Konfabulator was apparently written by some ex-Apple employes, and they had this to say:

Regarding the conspiracy theory about Konsposé and prior knowledge of Dashboard, here's the scoop. We knew Dashboard was coming, and we'd been told by *many* people that it was being developed as a "Konfabulator Killer". We never knew the specifics of it other than it was rumored to be the exact same thing as Konfabulator integrated at the system level. We didn't know that it was going to be touted as part of Exposé, and we didn't know that their format was going to be closer to a web page than a structured XML file.

The threat of having the OS subsume your original work is a threat Windows developers have lived with for years. I've always wondered what happened to WinZip and PKZip sales when Windows XP was introduced with integrated zip functionality.

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"biggest controversy"


"biggest controversy" 05/07/2004 03:29 AM

3G operators open up a VAT of
controversy


3G operators open up a VAT of
controversy
02/10/2004 02:55 AM
ZDNet UK Feb 9 2004 3:45PM GMT

Movable Type 3.0 Controversy


Movable Type 3.0 Controversy 05/17/2004 04:35 PM

MovableTyp e Madness: Dean over at blogs4God presents a really good wrap-up of the furor over the new Movable Type release.

Unbeknowst to me, Six Apart made a change over the weekend to say that mutiple Weblogs in MT used to create one site (for instance, if you have another blog to handle static pages for your site), do not count towards the Weblog limit in the license. They also removed a single CPU restriction that they said was in there by mistake, are allowing you to purchase additional blog/author packs for $10 each, and have increased the number of authors allowed in the mid-level version from 3 to 5.

Don Park links to some good resources as well, including this very wise column by Timothy Appnel over at O'Reilly:

As a developer and one who makes a living writing code, this reaction to Six Apart's new licensing is really disheartening and on a certain level frustrating to see. I am a firm believer and backer of free software. [...] I've personally released quite a bit of open source code myself and will continue to do so. However this apparent expectation of the vocal part of community that it is their right to have all great works of software at no cost is bothersome. If users don't have the funds or won't pay on principle for my time, effort or talent – how do I eat?

He makes a good point. Not everything in the world can be free, as much as we would like it. Yes, I love free software, but I also know when stuff is worth paying for. I'm reminded about what Nick Bradbury wrote in the pre-release FAQ to FeedDemon:

Will FeedDemon be free? Will it be open source? Sorry, no. I have nothing against open source, but I also have two kids to feed :)

I personally don't have a problem with Six Apart charging for this version. Movable Type was a gift so far, and I guess I never expected it to be free forever. I think they could have priced it a little lower, but it's still worth it.

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S.D. Library Web Site Controversy


S.D. Library Web Site Controversy 07/13/2004 03:44 PM

S.D. governor pulls plug on part of library Web site: Our governor, Mike Rounds, ordered some links removed from the youth section of the South Dakota State Library Web site this week because they linked to "inappropriate content." The governor's office isn't identifying the links, but sources say they were links to Planned Parenthood.

It's not censorship, Rounds said, because people can still see the content by going directly to the sites. Others will have to wait until state officials decide whether the sites are appropriate to be linked from a state page, he said.

People are upset.

"The governor is not the master father of the state of South Dakota," said Judith Krug, director of the American Library Association's Office for Intellectual Freedom. "At least I don't think he was elected on that basis."

I saw a group of people protesting outside the public library in downtown Sioux Falls yesterday. At the time, I didn't know what they were asking people to honk for. I didn't honk, just in case the signs read, "Honk if you're an eff-ing moron." That's happened to me once before.

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Other News: Konfabulator Controversy


Other News: Konfabulator Controversy 07/02/2004 10:04 AM
John Gruber weighs in with commentary on the WWDC Konfabulator-Dashboard dust-up.

Controversy Dogs Google


Controversy Dogs Google 03/24/2005 11:39 PM
ISEDB Mar 25 2005 3:53AM GMT

Coxib controversy rumbles on


Coxib controversy rumbles on 12/22/2004 01:22 AM

This weekend saw news that Celebrex, Pfizer’s coxib, in a trial looking at prevention of cancer, had 2.5 times the number of serious cardiovascular events compared to placebo. Curiously, another ongoing trial looking at cancer prevention has not shown the same risk increase, possibly in part due to the higher doses (400-800 mg/day compared to 400 mg/day) used.

Along with news from the world of pharamceuticals comes new data on ant pheromones, the Arctic Ocean, and much more in this edition of Science.Ars


Despite controversy, Google's auction is
a go


Despite controversy, Google's auction is
a go
08/13/2004 09:04 AM
Last-minute problems raise fears that the long-awaited public offering could be delayed--but the auction is set for Friday.

New Kazaa Could Ignite More Controversy


New Kazaa Could Ignite More Controversy 03/20/2003 01:05 PM
The owner of the widely used Kazaa file-swapping software, Sharman Networks, has launched a significantly expanded version of its controversial P2P (peer-to-peer) application. The updated version includes a playlist tool that enables users to download entire albums as easily as they previously downloaded single songs.

A Bridge Suspended in Controversy


A Bridge Suspended in Controversy 08/20/2004 06:47 AM
When an earthquake knocked down a section of the San Francisco-Oakland Bay Bridge, engineers vowed to make a stronger span. But years later, that plan is still mired in controversy. Part 2 of 2. By Amit Asaravala.
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